As a concert pianist, Nancy Weems has performed extensively in the United States and in Europe, Asia, Mexico, Central America, and the former Soviet Union. Selected as a United States Artistic Ambassador, Ms. Weems represented the United States in three international concert tours, and presented a solo debut recital at the John F. Kennedy Center for the Performing Arts in Washington, D.C. She has appeared as guest artist with numerous orchestras, and has given master classes in conservatories in the United States, Europe, Asia, and the West Indies. A graduate of Oberlin Conservatory and the University of Texas, Ms. Weems was an exchange professor and guest performer at the Royal Academy of Music in London; at Sungshin Women's University in Seoul, Korea; and in 2008, for the Kuala Lumpur International Master Classes in Malaysia. Ms. Weems has recorded for the Albany and the Bay Cities labels. The recording, "Classical Hollywood" was nominated for a Grammy award in 1990. In addition, she has been featured in recordings of American composers Arnold Rosner and Chris Theofanidis.

Currently, Nancy Weems is the Madison Endowed Professor of Piano and Coordinator of the Keyboard Area at the University of Houston Moores School of Music in Houston, Texas. Her students have won top awards in numerous state, national, and international piano competitions and many of her current and former students are now professional performers and teachers worldwide. Professor Weems was named the Outstanding Collegiate Teacher of the Year in l99l by the Texas Music Teachers Association, received a University of Houston Teaching Excellence Award in 1995, and was named the Moores School of Music Faculty of the Year in 2004.

Nancy Weems regularly presents lectures, recitals and teacher workshops and has been a featured MTNA convention artist for the states of New York, Washington, Minnesota, Utah, New Mexico, Arizona, Louisiana, South Carolina, Mississippi, Arkansas, Wyoming, and Texas. In addition, Ms. Weems has been a frequent presenter at the Music Teachers National Association Convention and the World Piano Pedagogy Conferences.